Enikeeva, R.F.; Kazantseva, A.V.; Davydova, Yu.D.; Mustafin, R.N.; Lobaskova, M.M.; Malykh, S.B.; Kovas, Yulia and Khusnutdinova, E.K.. 2022. Individual differences in the number of mitochondrial DNA copies: the effect of socio-demographic factors. Yakut Medical Journal(2), pp. 13-16. ISSN 1813-1905 [Article]

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Abstract or Description

Differences in mtDNA copy-number are caused by a complex effect of various environmental factors including chemical, biological or physiological stress, age, and embryonic development. However, to date it remains unknown, which factors and at what age have the most significant impact on mtDNA copy-number and cause greater allostatic load. Therefore, the present study aims to assess the involvement of various socio-demographic parameters in manifesting mtDNA copy-number in healthy individuals aged 18-25 years (N=1065). Within the framework of this study the effects of childhood maltreatment and age on individual differences in mitochondrial DNA copy number were revealed.

Item Type:	Article
Identification Number (DOI):	https://doi.org/10.25789/YMJ.2022.78.03
Additional Information:	In Russian
Keywords:	mitochondrial DNA, mitochondria, environmental factors, mitochondrial theory of aging, allostatic load
Departments, Centres and Research Units:	Psychology
Dates:	Date Event 30 January 2022 Accepted 30 June 2022 Published
Item ID:	33072
Date Deposited:	25 Jan 2023 09:28
Last Modified:	25 Jan 2023 09:28
Peer Reviewed:	Yes, this version has been peer-reviewed.
URI:	https://research.gold.ac.uk/id/eprint/33072

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