Phenotypic and genetic structure of anxiety sensitivity in adolescence and early adulthood.

Brown, H. M.; Trzaskowski, M.; Zavos, H. M. S.; Rijsdijk, Fruhling V.; Gregory, Alice M. and Eley, Thalia C.. 2012. Phenotypic and genetic structure of anxiety sensitivity in adolescence and early adulthood. Journal of Anxiety Disorders, 26, pp. 680-688. [Article]

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Abstract or Description

Anxiety sensitivity is a risk factor for emotional disorders. The structure of anxiety sensitivity was examined using phenotypic and genetic analyses. Self-reported anxiety sensitivity was measured at three time points from adolescence into young adulthood by 2651 individuals from the G1219 twin study. Confirmatory factor analyses revealed comparable statistical support for anxiety sensitivity models consisting of three or four dimensions across all time points. The three-factor model depicting Physical, Social and Mental anxiety-related concerns was favoured due to greater interpretability and parsimony. Multivariate quantitative genetic analyses supported a hierarchical structure with general genetic (.09-.61) and non-shared environmental (.39-.72) influences acting via a higher-order factor as well as dimension-specific genetic (.09-.21) and non-shared environmental (.23-.68) influences. The findings provide further evidence for a hierarchical structure underlying different dimensions of anxiety sensitivity.

Item Type:

Article

Departments, Centres and Research Units:

Psychology

Dates:

DateEvent
2012Published

Item ID:

7249

Date Deposited:

01 Oct 2012 14:34

Last Modified:

30 Jun 2017 15:19

Peer Reviewed:

Yes, this version has been peer-reviewed.

URI:

http://research.gold.ac.uk/id/eprint/7249

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