Genetic Influences on Anxiety in Children: What we've Learned and Where we're Heading

Gregory, Alice M. and Eley, Thalia C.. 2007. Genetic Influences on Anxiety in Children: What we've Learned and Where we're Heading. Clinical Child and Family Psychology Review, 10(3), pp. 199-212. ISSN 1095-4037 [Article]


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Abstract or Description

Anxiety is a common problem, typically beginning early in life. This article explores reasons for individual differences in levels of anxiety among children, by reviewing the genetic literature. The plethora of research to date has demonstrated clearly that both genes and environmental influences play important roles in explaining differences in levels of anxiety of various types among children. This has encouraged researchers to search for specific genes and environmental influences upon anxiety. Despite important progress in identifying links between

anxiety and specific genes—including associations between serotonin and dopamine genes and different symptoms of anxiety—overall, progress has been slow because multiple

genes of small effect size are likely to influence anxiety. This article explains how the hunt for genes involved in anxiety is likely to benefit from genetically sensitive research, which examines the co-occurrence of symptoms; includes measures of the environment; and examines

endophenotypes and risk pathways.

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anxiety; children; environment; genes; twins

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Date Deposited:

31 Jul 2008 11:41

Last Modified:

18 Mar 2021 05:12

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Yes, this version has been peer-reviewed.


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