Sadibolova, Renata; Monaldi, Luna and Terhune, Devin Blair. 2022. A proxy measure of striatal dopamine predicts individual differences in temporal precision. Psychonomic Bulletin & Review, 29(4), pp. 1307-1316. ISSN 1069-9384 [Article]

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Abstract or Description

The perception of time is characterized by pronounced variability across individuals, with implications for a diverse array of psychological functions. The neurocognitive sources of this variability are poorly understood, but accumulating evidence suggests a role for inter-individual differences in striatal dopamine levels. Here we present a pre-registered study that tested the predictions that spontaneous eyeblink rates, which provide a proxy measure of striatal dopamine availability, would be associated with aberrant interval timing (lower temporal precision or overestimation bias). Neurotypical adults (N = 69) underwent resting state eye tracking and completed visual psychophysical interval timing and control tasks. Elevated spontaneous eyeblink rates were associated with poorer temporal precision but not with inter-individual differences in perceived duration or performance on the control task. These results signify a role for striatal dopamine in variability in human time perception and can help explain deficient temporal precision in psychiatric populations characterized by elevated dopamine levels.

Item Type:	Article
Identification Number (DOI):	https://doi.org/10.3758/s13423-022-02077-1
Additional Information:	This research was supported in part by grant from the Biotechnology and Biological Sciences Research Council, grant number: BB/R01583X/1. Open practices statement: The data and materials are available at https://osf.io/jxc3f. The study was preregistered (https://osf.io/fzdbv).
Keywords:	Dopamine, Eye-tracking, Temporal cognition, Time perception, Schizophrenia
Departments, Centres and Research Units:	Psychology
Dates:	Date Event 2 March 2022 Accepted 22 March 2022 Published Online August 2022 Published
Funders:	Funding body Funder ID Grant Number Biotechnology and Biological Sciences Research Council UNSPECIFIED BB/R01583X/1
Item ID:	31660
Date Deposited:	23 Mar 2022 09:26
Last Modified:	15 Sep 2022 09:16
Peer Reviewed:	Yes, this version has been peer-reviewed.
URI:	https://research.gold.ac.uk/id/eprint/31660

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