Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease.

Nitkunan, Arani; Charlton, Rebecca A; Barrick, Thomas R; McIntyre, Dominick J O; Howe, Franklyn A and Markus, Hugh S. 2009. Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease. NMR in biomedicine, 22(3), pp. 285-91. ISSN 0952-3480 [Article]

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Abstract or Description

The most consistent change in SVD is a reduction in NAA, a marker of neuronal integrity. The lack of correlation with cognition does not support the use of MRS as a surrogate disease marker.

Item Type:

Article

Departments, Centres and Research Units:

Psychology

Dates:

DateEvent
April 2009Published

Item ID:

8326

Date Deposited:

09 Jun 2013 12:47

Last Modified:

30 Jun 2017 14:11

Peer Reviewed:

Yes, this version has been peer-reviewed.

URI:

https://research.gold.ac.uk/id/eprint/8326

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