Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease.
Nitkunan, Arani; Charlton, Rebecca A; Barrick, Thomas R; McIntyre, Dominick J O; Howe, Franklyn A and Markus, Hugh S. 2009. Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease. NMR in biomedicine, 22(3), pp. 285-91. ISSN 0952-3480 [Article]
No full text availableAbstract or Description
The most consistent change in SVD is a reduction in NAA, a marker of neuronal integrity. The lack of correlation with cognition does not support the use of MRS as a surrogate disease marker.
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8326 |
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09 Jun 2013 12:47 |
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30 Jun 2017 14:11 |
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Yes, this version has been peer-reviewed. |
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